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The Department of Surgery dates from the establishment of the Faculty of Medicine in 1854, when Dr. James Sampson was appointed the first Professor of Clinical Medicine and Surgery. Today, the Department consists of eight separate surgical divisions: Cardiac, General, Neurosurgery, Orthopaedics, Plastics, Thoracic, Vascular and Maxillofacial. The Department has 32 full-time faculty plus numerous adjuncts and is accredited for the subspeciality resident training hospitals: the Kingston General Hospital and the Hotel Dieu Hospital. Faculty and residents provide tertiary care for patients at these hospitals, as well as being involved in a variety of research endeavours in surgery. The main office of the Department is located in Kingston General Hospital.

Spanish and Italian were first taught at Queen's University at Kingston, early in the 20th century in the former Department of Romance Languages. The Department of Spanish and Italian was formed in 1920 under the guidance of Professor J.H. Brovedani, who remained Head of the Department until 1949. The Department offers a comprehensive range of courses in the language, literature, and culture of Spain, Latin America, and Italy, as well as a Master's program in Spanish (Peninsular and Latin American literature). It offers, at the undergraduate level, a major in Spanish, a medial in Italian, and administers an honours degree in Spanish and Latin American Studies. While the number of full-time faculty has dropped slightly in recent years from its traditional number of six, the number of undergraduate students has doubled. The increase is partly due to the demand for language proficiency in professional faculties, and an awareness of the growing importance of Latin America, especially in its dealings with Canada. The Department, located in Kingston Hall, is part of the Faculty of Arts and Science.

A large block was purchased by the Province in 1850 for a normal school which is now part of Ryerson Polytechnic University. Here Egerton Ryerson superintended the work of the first Department of Public Instruction in Upper Canada. Here generations of teachers prepared themselves for careers in education.
In October of 1844, Sir Charles Metcalfe, the head of administrative affairs in the province, appointed Rev. Dr. Egerton Ryerson to the position of Chief Superintendent of Education for Upper Canada, the highest position in the Department of Public Instruction for Upper Canada. For the next thirty years he would have a dramatic impact on the development of education in Ontario. Shortly after Ryerson accepted the position of Chief Superintendent he appointed Dr. John George Hodgins as the Chief Clerk for the Department of Public Instruction. The latter worked closely with Ryerson to build the foundations of the education system, advising him on major issues and assisting with the wording of legislation.
In 1855, Hodgins was appointed Deputy Head of the Department of Public Instruction, and later (in 1890) was appointed the Librarian and Historiographer to the Department. During his sixty plus years with the Department, Hodgins wrote voluminously on the topic of Ontario's educational history and school architecture.